Molecular Maps

Mapping Molecular Landscapes



Image: Bang Wong/Broad Communication

Researchers have used the latest genomic tools to map out the epigenetic landscape, which is shaped by DNA methylation and modifications to histone proteins. They have also examined the role that these marks may play in cellular reprogramming.



"Much of the field of stem cell biology and development remains uncharted territory. Just as famous explorers and astronomers mapped out landmasses and constellations, researchers are working fervently to chart the molecular landscapes within stem cells -- especially embryonic stem cells. A clearer understanding of the cells' unique properties, particularly their ability to give rise to nearly any type of cell, could unlock fundamental questions about biology and may even spur novel ways to treat disease."

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